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The Food and Drug Administration, FDA, has approved the drug Vivitrol for that treatment of opioid dependence as outlined by a news release by them on 10-12-2010. Using two separate drugs to shed pounds can be very effective you'll find combinations before the FDA now awaiting approval. When dealing with fat loss and the those who go through it one should err to the side of caution and let the FDA do its job and demand some research be done in order that the public understands the side effects and dangers of the medications before we take them. Keep in mind that drug companies will be in business to generate money and that they would say anything to keep people on the medications. Researchers found out that participants taking this drug for any year, dropped excess weight within one month and have kept the body weight off during the entire 56 weeks from the study. Contrave is a combination in the drugs naltrexone and bupropion, which appears to reflect a brand new trend of weight-loss drugs which are made up of several active ingredient, which may make them more effective and safer. Combo-pilling may be the newest fad or even better the newest into the future under scrutiny and thus it is just more publicly known lately, comb-pilling for losing weight has been around since the eighties. The biggest reason that using a combination of pills is now popular may be the fact that as of right now there are no long term prescription slimming capsules that have been approved by the FDA besides orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications and some of the combinations are already rejected or have yet to be authorized by the FDA. Seizures certainly are a side effect with Contrave and really should not be taken in people who have seizure disorders. The drug also can raise blood pressure and heartbeat, and shouldn't be used in people who have a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise hypertension and heartbeat and must 't be used in patients with uncontrolled high blood pressure, and also by a person with heart-related and cerebrovascular (circulatory dysfunction impacting the mind) disease. Patients which has a history of heart attack or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes having a boxed warning to alert physicians and patients towards the increased chance of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stop smoking. "This may be the first drug I'm mindful of that targets both the appetite and reward centres in the brain," he was quoted saying.